Cranial Nerves - Horse Anatomy | Inside The Equine
Nervous System

Cranial Nerves

Nervi craniales

Overview

The 12 pairs of cranial nerves emerge directly from the brain and brainstem and are responsible for sensory, motor, and parasympathetic functions of the head and some viscera. In horses, several cranial nerves have unique clinical significance: the vagus nerve (CN X) gives rise to the recurrent laryngeal nerve critical for laryngeal function; CN VII (facial) is vulnerable to external trauma; and CN IX, X, XI, XII are at risk from guttural pouch disease; a condition unique to equids. The guttural pouches are diverticula of the auditory tubes that surround the internal carotid artery and major cranial nerves, making guttural pouch infections potentially life-threatening.

Clinical Significance

There are 12 pairs of cranial nerves. A systematic cranial nerve exam evaluates: CN I (olfaction), CN II (menace response, PLR), CN III/IV/VI (pupil, strabismus, eye movement), CN V (facial sensation, jaw tone), CN VII (facial symmetry, ear/eyelid/lip movement), CN VIII (vestibular function, hearing), CN IX/X (swallow, laryngeal function, guttural pouch), CN XI (trapezius/brachiocephalic), CN XII (tongue symmetry/tone). The guttural pouches are unique to equids and are clinically critical because CN IX, X, XI, XII, and the internal carotid artery traverse their walls.

Common Conditions & Injuries

Facial Nerve Paralysis (CN VII)

Dysfunction of the facial nerve, commonly from halter pressure (at the facial crest), guttural pouch disease, temporohyoid osteoarthropathy, or EPM. The facial nerve is superficial where it crosses th

Guttural Pouch Mycosis

Fungal infection of the guttural pouch, potentially eroding into the internal carotid artery.

Vestibular Disease (CN VIII)

Dysfunction of the vestibulocochlear nerve causing balance disturbances. Peripheral (inner ear, nerve) causes include THO, otitis media/interna, and guttural pouch disease. Central causes include EPM

Trigeminal Neuritis (CN V)

Inflammation of the trigeminal nerve, which may occur with polyneuritis equi or idiopathically. Causes denervation of the muscles of mastication.

Temporohyoid osteoarthropathy

Progressive proliferative osteoarthropathy of the temporohyoid joint that may cause fusion of the joint and fracture of the petrous temporal bone, damaging CN VII and CN VIII as they traverse the bone

Frequently Asked Questions

What is Facial Nerve Paralysis (CN VII) in horses?

Dysfunction of the facial nerve, commonly from halter pressure (at the facial crest), guttural pouch disease, temporohyoid osteoarthropathy, or EPM. The facial nerve is superficial where it crosses the mandible, making it vulnerable to external compression. Signs include: Lip droop on affected side; ear droop; inability to close eyelid (exposure keratitis risk); feed accumulation in cheek; muzzle deviation to unaffected side

What is Guttural Pouch Mycosis in horses?

Fungal infection of the guttural pouch, potentially eroding into the internal carotid artery. Signs include: Epistaxis (can be fatal); nasal discharge; difficulty swallowing; cranial nerve deficits

What is Vestibular Disease (CN VIII) in horses?

Dysfunction of the vestibulocochlear nerve causing balance disturbances. Peripheral (inner ear, nerve) causes include THO, otitis media/interna, and guttural pouch disease. Central causes include EPM and EHV-1. Signs include: Head tilt toward affected side; horizontal or rotary nystagmus; circling; ataxia with falling/leaning to affected side; strabismus (ventral deviation of ipsilateral eye)

What is Trigeminal Neuritis (CN V) in horses?

Inflammation of the trigeminal nerve, which may occur with polyneuritis equi or idiopathically. Causes denervation of the muscles of mastication. Signs include: Bilateral masseter and temporalis atrophy ('sunken face'); inability to close mouth (dropped jaw); difficulty prehending and chewing feed; weight loss

What is Temporohyoid osteoarthropathy in horses?

Progressive proliferative osteoarthropathy of the temporohyoid joint that may cause fusion of the joint and fracture of the petrous temporal bone, damaging CN VII and CN VIII as they traverse the bone. Signs include: Consult veterinarian for specific symptoms.; Head shaking; difficulty eating; ear rubbing; acute onset vestibular signs (head tilt, nystagmus, circling); facial nerve paralysis; keratitis (corneal ulceration from inability to blink)

What are the clinical concerns for the Cranial Nerves?

There are 12 pairs of cranial nerves. A systematic cranial nerve exam evaluates: CN I (olfaction), CN II (menace response, PLR), CN III/IV/VI (pupil, strabismus, eye movement), CN V (facial sensation, jaw tone), CN VII (facial symmetry, ear/eyelid/lip movement), CN VIII (vestibular function, hearing), CN IX/X (swallow, laryngeal function, guttural pouch), CN XI (trapezius/brachiocephalic), CN XII (tongue symmetry/tone). The guttural pouches are unique to equids and are clinically critical because CN IX, X, XI, XII, and the internal carotid artery traverse their walls.

Explore This Structure in 3D

See the Cranial Nerves on our interactive 3D horse model. Open 3D Model