Equine Degenerative Myeloencephalopathy (EDM) in Horses

Equine Degenerative Myeloencephalopathy (EDM)

Overview

Diffuse neuraxonal dystrophy affecting the brainstem and spinal cord, associated with vitamin E deficiency in genetically predisposed horses. Neuroaxonal dystrophy (eNAD) is the milder early form.

Signs & Symptoms

Symmetric ataxia and weakness in all four limbs (hindlimbs worse); onset before 2 years of age; abnormal base-wide stance; hypermetric gait; no cranial nerve deficits

Affected Structures

Frequently Asked Questions

What is Equine Degenerative Myeloencephalopathy (EDM) in horses?

Diffuse neuraxonal dystrophy affecting the brainstem and spinal cord, associated with vitamin E deficiency in genetically predisposed horses. Neuroaxonal dystrophy (eNAD) is the milder early form.

What are the signs of Equine Degenerative Myeloencephalopathy (EDM)?

Symmetric ataxia and weakness in all four limbs (hindlimbs worse); onset before 2 years of age; abnormal base-wide stance; hypermetric gait; no cranial nerve deficits