Gastric Squamous Cell Carcinoma

Overview

## Overview Gastric squamous cell carcinoma is the most common stomach tumor in horses. It arises in the squamous (non-glandular) region and is highly metastatic. Clinical signs are nonspecific: progressive weight loss, low-grade colic, intermittent fever, anemia, and low protein. Gastroscopy reveals an irregular ulcerated mass. ## Causes Unknown. Equine papillomavirus type 2 has been identified in some lesions. ## Diagnosis Gastroscopy with biopsy. Abdominal ultrasound may show metastasis or effusion. Bloodwork often shows anemia and hypoproteinemia. ## Treatment No effective treatment. Palliative care only. Most horses are euthanized once diagnosed. ## Recovery and Prognosis Grave. Metastasis is common at diagnosis. ## Prevention None.

Signs & Symptoms

progressive weight loss; chronic low-grade colic; intermittent fever; anemia; hypoproteinemia; ulcerated mass on gastroscopy

Affected Structures

Frequently Asked Questions

What is Gastric Squamous Cell Carcinoma in horses?

## Overview Gastric squamous cell carcinoma is the most common stomach tumor in horses. It arises in the squamous (non-glandular) region and is highly metastatic. Clinical signs are nonspecific: progressive weight loss, low-grade colic, intermittent fever, anemia, and low protein. Gastroscopy reveals an irregular ulcerated mass. ## Causes Unknown. Equine papillomavirus type 2 has been identified in some lesions. ## Diagnosis Gastroscopy with biopsy. Abdominal ultrasound may show metastasis or effusion. Bloodwork often shows anemia and hypoproteinemia. ## Treatment No effective treatment. Palliative care only. Most horses are euthanized once diagnosed. ## Recovery and Prognosis Grave. Metastasis is common at diagnosis. ## Prevention None.

What are the signs of Gastric Squamous Cell Carcinoma?

progressive weight loss; chronic low-grade colic; intermittent fever; anemia; hypoproteinemia; ulcerated mass on gastroscopy