Squamous Cell Carcinoma in Horses | Inside The Equine

Squamous Cell Carcinoma

Overview

Malignant tumor of keratinocytes, the second most common equine skin cancer. UV radiation is the primary risk factor. Most common on unpigmented skin; especially eyelids (most frequent ocular tumor), penis/prepuce, vulva, and perineum. Breeds at higher risk include Appaloosas, Paints, Cremellos, and draft crosses with pink skin.

Signs & Symptoms

Non-healing ulcerated or proliferative lesion on unpigmented skin; crusty, bleeding mass; commonly affects third eyelid, eyelid margin, penis, prepuce, or vulva; locally invasive; may metastasize to regional lymph nodes (10–20%); penile SCC may cause dysuria or hemorrhagic discharge

Affected Structures

Frequently Asked Questions

What is Squamous Cell Carcinoma in horses?

Malignant tumor of keratinocytes, the second most common equine skin cancer. UV radiation is the primary risk factor. Most common on unpigmented skin; especially eyelids (most frequent ocular tumor), penis/prepuce, vulva, and perineum. Breeds at higher risk include Appaloosas, Paints, Cremellos, and draft crosses with pink skin.

What are the signs of Squamous Cell Carcinoma?

Non-healing ulcerated or proliferative lesion on unpigmented skin; crusty, bleeding mass; commonly affects third eyelid, eyelid margin, penis, prepuce, or vulva; locally invasive; may metastasize to regional lymph nodes (10–20%); penile SCC may cause dysuria or hemorrhagic discharge