Urticaria (Hives) in Horses | Inside The Equine

Urticaria (Hives)

Overview

Type I hypersensitivity reaction causing localized dermal edema. Very common in horses. Triggers include insect bites, medications (especially NSAIDs, antibiotics), vaccines, feed allergens, contact allergens (bedding, topical products), inhaled allergens, and stress. Usually self-limiting (12–24 hours) but may recur if the allergen is not identified.

Signs & Symptoms

Multiple raised, round to irregular wheals (2–20 cm) appearing rapidly over the neck, trunk, and hindquarters; may pit on pressure; usually non-pruritic; skin between wheals is normal; angioedema (deeper swelling) may affect muzzle, eyelids, or distal limbs; rarely may accompany anaphylaxis with respiratory distress

Affected Structures

Frequently Asked Questions

What is Urticaria (Hives) in horses?

Type I hypersensitivity reaction causing localized dermal edema. Very common in horses. Triggers include insect bites, medications (especially NSAIDs, antibiotics), vaccines, feed allergens, contact allergens (bedding, topical products), inhaled allergens, and stress. Usually self-limiting (12–24 hours) but may recur if the allergen is not identified.

What are the signs of Urticaria (Hives)?

Multiple raised, round to irregular wheals (2–20 cm) appearing rapidly over the neck, trunk, and hindquarters; may pit on pressure; usually non-pruritic; skin between wheals is normal; angioedema (deeper swelling) may affect muzzle, eyelids, or distal limbs; rarely may accompany anaphylaxis with respiratory distress