## Overview Splenic lymphosarcoma is infiltration of the spleen by malignant lymphocytes. The spleen is frequently involved in the multicentric form of equine lymphoma. Signs include an enlarged spleen palpable on rectal examination, weight loss, anemia, intermittent fever, and elevated globulins. Other organs are often affected simultaneously. ## Causes Lymphoid neoplasia. ## Diagnosis Rectal palpation, ultrasound, and biopsy or cytology. ## Treatment Palliative corticosteroids or chemotherapy. Prognosis is poor. ## Recovery and Prognosis Poor. Survival is typically weeks to months. ## Prevention None.
enlarged spleen palpable per rectum; weight loss; anemia; intermittent fever; hyperglobulinemia
## Overview Splenic lymphosarcoma is infiltration of the spleen by malignant lymphocytes. The spleen is frequently involved in the multicentric form of equine lymphoma. Signs include an enlarged spleen palpable on rectal examination, weight loss, anemia, intermittent fever, and elevated globulins. Other organs are often affected simultaneously. ## Causes Lymphoid neoplasia. ## Diagnosis Rectal palpation, ultrasound, and biopsy or cytology. ## Treatment Palliative corticosteroids or chemotherapy. Prognosis is poor. ## Recovery and Prognosis Poor. Survival is typically weeks to months. ## Prevention None.
enlarged spleen palpable per rectum; weight loss; anemia; intermittent fever; hyperglobulinemia