Lien (Splen)
The equine spleen is a large, tongue-shaped organ weighing 1-2 kg located on the left side of the abdomen, attached to the stomach by the gastrosplenic ligament and to the left kidney by the nephrosplenic ligament. It is the largest lymphoid organ in the body and serves dual functions: as a secondary lymphoid organ filtering blood-borne antigens and as a blood storage reservoir unique in its capacity among domestic species. The equine spleen can store up to 12 liters of red blood cells (approximately one-third of the total RBC volume), which are released into circulation during exercise or excitement by capsular smooth muscle contraction under sympathetic control.
The equine spleen serves as both a lymphoid organ and a massive blood reservoir. During exercise, sympathetic stimulation causes splenic contraction, releasing 6-12 liters of stored red blood cells into circulation; this can increase the PCV from ~35% at rest to ~60-65% during maximal exercise. The spleen is assessed by transabdominal ultrasound (left side) and rectal palpation (nephrosplenic ligament and caudal border). The nephrosplenic space between the spleen and left kidney is the site of nephrosplenic entrapment of the large colon.
Traumatic or spontaneous rupture of the spleen causing hemoabdomen. May result from blunt trauma (kick, fall), neoplasia (hemangiosarcoma, lymphosarcoma), or idiopathic causes.
Neoplastic infiltration of the spleen by malignant lymphocytes. The spleen is frequently involved in the multicentric form of equine lymphosarcoma.
Malignant neoplasm of vascular endothelium. Less common than in dogs but can occur in horses. Risk of spontaneous hemorrhage.
Focal abscessation within the splenic parenchyma, usually hematogenous in origin (Streptococcus spp., S. equi; bastard strangles). May also occur secondary to migrating foreign bodies.
Traumatic or spontaneous rupture of the spleen causing hemoabdomen. May result from blunt trauma (kick, fall), neoplasia (hemangiosarcoma, lymphosarcoma), or idiopathic causes. Signs include: Acute colic; tachycardia; pale mucous membranes; prolonged CRT; weakness/collapse; peritoneal fluid serosanguineous to hemorrhagic on abdominocentesis; dropping PCV
Neoplastic infiltration of the spleen by malignant lymphocytes. The spleen is frequently involved in the multicentric form of equine lymphosarcoma. Signs include: Splenomegaly (enlarged spleen palpable per rectum); weight loss; anemia; intermittent fever; hyperglobulinemia; may have concurrent lymph node and liver involvement
Malignant neoplasm of vascular endothelium. Less common than in dogs but can occur in horses. Risk of spontaneous hemorrhage. Signs include: Recurrent colic episodes; episodic weakness; hemoabdomen; progressively dropping PCV; large splenic mass on ultrasound
Focal abscessation within the splenic parenchyma, usually hematogenous in origin (Streptococcus spp., S. equi; bastard strangles). May also occur secondary to migrating foreign bodies. Signs include: Intermittent fever; weight loss; recurrent colic; elevated fibrinogen and white cell count; hypoechoic mass within spleen on ultrasound
The equine spleen serves as both a lymphoid organ and a massive blood reservoir. During exercise, sympathetic stimulation causes splenic contraction, releasing 6-12 liters of stored red blood cells into circulation; this can increase the PCV from ~35% at rest to ~60-65% during maximal exercise. The spleen is assessed by transabdominal ultrasound (left side) and rectal palpation (nephrosplenic ligament and caudal border). The nephrosplenic space between the spleen and left kidney is the site of nephrosplenic entrapment of the large colon.
See the Spleen on our interactive 3D horse model. Open 3D Model