Spleen - Horse Anatomy | Inside The Equine
Lymphatic System

Spleen

Lien (Splen)

Overview

The equine spleen is a large, tongue-shaped organ weighing 1-2 kg located on the left side of the abdomen, attached to the stomach by the gastrosplenic ligament and to the left kidney by the nephrosplenic ligament. It is the largest lymphoid organ in the body and serves dual functions: as a secondary lymphoid organ filtering blood-borne antigens and as a blood storage reservoir unique in its capacity among domestic species. The equine spleen can store up to 12 liters of red blood cells (approximately one-third of the total RBC volume), which are released into circulation during exercise or excitement by capsular smooth muscle contraction under sympathetic control.

Clinical Significance

The equine spleen serves as both a lymphoid organ and a massive blood reservoir. During exercise, sympathetic stimulation causes splenic contraction, releasing 6-12 liters of stored red blood cells into circulation; this can increase the PCV from ~35% at rest to ~60-65% during maximal exercise. The spleen is assessed by transabdominal ultrasound (left side) and rectal palpation (nephrosplenic ligament and caudal border). The nephrosplenic space between the spleen and left kidney is the site of nephrosplenic entrapment of the large colon.

Common Conditions & Injuries

Splenic Rupture / Hematoma

Traumatic or spontaneous rupture of the spleen causing hemoabdomen. May result from blunt trauma (kick, fall), neoplasia (hemangiosarcoma, lymphosarcoma), or idiopathic causes.

Splenic Lymphosarcoma

Neoplastic infiltration of the spleen by malignant lymphocytes. The spleen is frequently involved in the multicentric form of equine lymphosarcoma.

Splenic Hemangiosarcoma

Malignant neoplasm of vascular endothelium. Less common than in dogs but can occur in horses. Risk of spontaneous hemorrhage.

Splenic Abscess

Focal abscessation within the splenic parenchyma, usually hematogenous in origin (Streptococcus spp., S. equi; bastard strangles). May also occur secondary to migrating foreign bodies.

Frequently Asked Questions

What is Splenic Rupture / Hematoma in horses?

Traumatic or spontaneous rupture of the spleen causing hemoabdomen. May result from blunt trauma (kick, fall), neoplasia (hemangiosarcoma, lymphosarcoma), or idiopathic causes. Signs include: Acute colic; tachycardia; pale mucous membranes; prolonged CRT; weakness/collapse; peritoneal fluid serosanguineous to hemorrhagic on abdominocentesis; dropping PCV

What is Splenic Lymphosarcoma in horses?

Neoplastic infiltration of the spleen by malignant lymphocytes. The spleen is frequently involved in the multicentric form of equine lymphosarcoma. Signs include: Splenomegaly (enlarged spleen palpable per rectum); weight loss; anemia; intermittent fever; hyperglobulinemia; may have concurrent lymph node and liver involvement

What is Splenic Hemangiosarcoma in horses?

Malignant neoplasm of vascular endothelium. Less common than in dogs but can occur in horses. Risk of spontaneous hemorrhage. Signs include: Recurrent colic episodes; episodic weakness; hemoabdomen; progressively dropping PCV; large splenic mass on ultrasound

What is Splenic Abscess in horses?

Focal abscessation within the splenic parenchyma, usually hematogenous in origin (Streptococcus spp., S. equi; bastard strangles). May also occur secondary to migrating foreign bodies. Signs include: Intermittent fever; weight loss; recurrent colic; elevated fibrinogen and white cell count; hypoechoic mass within spleen on ultrasound

What are the clinical concerns for the Spleen?

The equine spleen serves as both a lymphoid organ and a massive blood reservoir. During exercise, sympathetic stimulation causes splenic contraction, releasing 6-12 liters of stored red blood cells into circulation; this can increase the PCV from ~35% at rest to ~60-65% during maximal exercise. The spleen is assessed by transabdominal ultrasound (left side) and rectal palpation (nephrosplenic ligament and caudal border). The nephrosplenic space between the spleen and left kidney is the site of nephrosplenic entrapment of the large colon.

Explore This Structure in 3D

See the Spleen on our interactive 3D horse model. Open 3D Model